The Sydney Roosters squad have been assessed by Club medical staff following Thursday's match against Melbourne Storm.
Lachlan Lam was forced from the field in the first half and was unable to return to the match.
Scans have confirmed a syndesmosis injury that will require Lam to undergo a surgical procedure early next week.
Mitchell Aubusson sustained a significant ligament tear in his left wrist that forced him from the field late in the first half.
There is currently no definite prognosis, as his wrist needs to be reviewed by a specialist early next week.
Luke Keary sustained a fractured rib that forced him from the field, and has since been cleared of any associated internal injuries.
Josh Morris made a successful return to the field after missing the last two weeks with a minor calf complaint.